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The prevalence of GAD after stroke was 28%in the acute stage,and there was no significant decrease through the 3 years of follow-up.At 1 year,only 23%of the patients with early GAD(0 to 3 months)had recovered;those not recovered at this follow-up had a high risk of a chronic development of the anxiety disorder.Comorbidity with major depression was high and seemed to impair the prognosis of depression.At the acute stage after stroke,GAD plus depression was associated with left hemispheric lesion,whereas anxiety alone was associated with right hemispheric lesion.Cerebral atrophy was associated with both depression and anxiety disorder late but not early after stroke.Dependence in activities of daily living and reduced social network were associated with GAD at all follow-up periods except at the acute stage.GAD after stroke is a common and long-lasting affliction that interferes substantially with social life and functional recovery.There is a differentiation of factors implicated in its development based on the period of time since the stroke event. |
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